For over a decade, scientists have been growing organoids - small clusters of cells that mimic a particular organ - to serve as miniature biological models. Organoids of the brain have been used to ...

Hierarchical structure of muscle and activation of thin filaments. In both skeletal and cardiac muscles under a relaxed state, a low intracellular calcium ion concentration is maintained and the ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Cardiac complications in Duchenne muscular dystrophy (DMD) are the result of cardiac muscle involvement that accompanies the deterioration of skeletal muscle in the disease. The use of ...