Researchers have mapped out the proteins implicated in the early stages of motor neurone disease (MND). They have developed a longitudinal map of the proteins involved in MND across the trajectory of ...

Pictured are nuclei of induced pluripotent stem cell (iPSC)-derived motor neurons stained for contrast. The nucleus on the left has been treated with DMSO (control) and appears mostly blue. The ...

Dr Sophie Burling used her doctoral research to create a new patient-specific model of motor neurone disease, laying the groundwork for future treatments that could improve quality of life for people ...

Motor neurons are some of the largest cells in the human body. In particular, upper neurons—extending from the cerebral cortex to the brain stem or spinal cord—average 60μm in diameter. 3,4 These ...

Signals relayed to motor neurons from the brain enable muscle movement, but these signals typically pass through spinal interneurons before they reach their destination. How the brain and this highly ...

What is the cause of flexor and extensor spasms seen in patients with paraplegia? What is the prognosis in such patients? How do we manage such a problem? In a spinal cord injury resulting in ...