Histology of growth plate cartilage of achondroplasia model mice in which FGFR3 is overactivated. This study identified SPONDIN1 as a marker for CREB activity. Resting zone was expanded and expressed ...

Cell- and animal-based models of bone formation reveal novel mechanisms involved in the cartilage-to-bone phenotype ...

Bone growth occurs through the proliferation of specialized cells of the cartilage tissue, known as chondrocytes, on either end of a bone. This process requires the synthesis of extracellular matrix ...

DNA can help to stimulate bone healing in a localized and targeted manner, for example after a complicated fracture or after severe tissue loss following surgery. Scientists have developed a new ...

A bone-like composite developed at EPFL uses naturally occurring enzymes to accelerate mineralization through an energy-efficient, room-temperature process. The strong, lightweight material shows ...

Growth plates are areas of cartilage found at the ends of long bones. They play a role in the bone growth of children and teens. An injury to a growth plate can affect the development of a bone. While ...